New light and sound methods let scientists control gene edits in mice

Scientists have successfully used light and sound to control CRISPR gene-editing tools and make targeted changes to the genome in specific tissues in mice. The method uses viral particles to carry light-controlled gene editors directly into cells.

Context

Controlling where gene editors work inside a living body is a major goal for medical research, as it helps prevent unintended edits in healthy parts. Such laboratory studies in mice help researchers understand how to make genetic treatments safer before any future human applications.